Over the past 10 plus years, I have been blessed to learn a skill that has a multitude of uses from oil and gas exploration (where I first learned and used GIS) to archaeology and environmental (my current GIS consulting area). But GIS has a wide range of uses that can be used cross-platform and cross-industries. Take, for example, health care and business. Walgreens is a heavy GIS user that has integrated the use and practice of GIS to be able to predict within a day or two where influenza outbreaks are occurring. The CDC is usually a week or more in detecting the outbreaks and occurrences of influenza.
Also another great article: WalMap: The App By Walgreens That Maps Out Community Trends in Real Time